PE22-28 - UK Peptides
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PE22-28

£69.00

Looking for a Certificate of Analysis?
If you are looking for a Certificate Of Analysis, please email research@peptidesuk.co.uk to have it sent to you.

Please Note: Many sites are displaying counterfeit COAs, so ours is provided upon request.

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Product Description

PE22-28 is a synthetic analog of spadin, a peptide derived from the sortilin-related receptor (SorCS2) propeptide. It is studied for its potent antidepressant-like effects and neuroprotective properties. PE22-28 modulates TREK-1 potassium channels, which are implicated in mood regulation and neuronal excitability, making it of significant interest in preclinical models of depression and neurological disorders.

Benefits (Based on Preclinical Research)

  • Rapid-acting antidepressant effects in animal models

  • Blocks TREK-1 potassium channels linked to depression

  • Enhances neurogenesis and synaptic plasticity

  • Reduces anxiety and improves stress resilience

  • Studied in mood disorders, cognitive impairment, and neuroinflammation

Who Uses This
Neuroscientists and pharmacology researchers use PE22-28 in studies targeting novel antidepressant mechanisms and exploring neuronal repair strategies.

Why Choose PE22-28

  • Fast-onset neuropeptide targeting mood pathways

  • Supplied sterile and lyophilized for laboratory reconstitution

  • Verified for purity and molecular identity with COA

  • Suitable for CNS, psychiatric, and neurodegeneration models

Documentation and Quality
Each batch is lab-tested and shipped under validated cold-chain protocols. Includes Certificate of Analysis, HPLC, and MS data.

Disclaimer
PE22-28 is intended strictly for research use only. Not approved for human use or therapeutic application. For handling by qualified laboratories and licensed research professionals.

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