IGF-1LR3

Product Description

IGF-1 LR3 is a recombinant analog of human IGF-1 (Insulin-like Growth Factor-1) engineered for extended half-life and enhanced biological activity. It features a 13-amino-acid N-terminal extension and an arginine substitution at position 3, which reduces binding to IGF-binding proteins (IGFBPs), leading to greater free-circulating IGF-1 and more potent tissue response. IGF-1 LR3 is widely studied in muscle growth, injury recovery, cellular proliferation, and anti-aging models.

Benefits (Based on Preclinical Research)

• Increases muscle hypertrophy and myoblast proliferation

• Enhances protein synthesis and nitrogen retention

• Promotes tissue regeneration and wound healing

• Supports cellular longevity and neurogenesis

• Reduces muscle wasting in atrophy models

Who Uses This

IGF-1 LR3 is used in research exploring muscle development, recovery after trauma, neuroregeneration, and cellular aging. It is highly relevant in both sports science and biomedical regeneration studies.

Why Choose IGF-1 LR3

• 2–3x longer half-life than native IGF-1

• Reduced IGFBP binding = increased free IGF-1

• Supplied sterile, lyophilized, and COA-verified

• Effective for long-duration tissue and cellular studies

Documentation and Quality

Each batch is accompanied by a full Certificate of Analysis and independently tested via HPLC and Mass Spectrometry. Shipped under validated cold-chain conditions to preserve structural stability.

Disclaimer

IGF-1 LR3 is intended for research use only. It is not approved for human or veterinary use. Access restricted to certified laboratories and research professionals.